Oxygen Bar

“We're all addicted to oxygen.”
The Chemical Buddha was called all sorts of things: drunk, druggie, pothead, junkie, burn out, stoner, etc. And if he wasn’t too fucked up to do it, he would usually point out how we’re all addicted to something. He just had more going for himself than anyone else. It was one particularly inspiring moment when he it dawned on him that every animal on the planet (of which we were one) was addicted to oxygen. When he awoke to this insight, he would berate his detractors and say, "Just see how long you can go without oxygen and tell me you’re not an addict too!" He would also point out oxygen withdrawals lead to death. So you could say we’re all genetically disposed to be addicted to oxygen.
What can you not do without?
How do you feel when you don’t have it anymore and how do you adjust?